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Figure 3 | Molecular Neurodegeneration

Figure 3

From: Prolonged Aβ treatment leads to impairment in the ability of primary cortical neurons to maintain K+ and Ca2+ homeostasis

Figure 3

Neuronal viability in response to glutamate treatment following seven days of daily Aβ 1-40 treatment. Treatment with glutamate significantly reduced neuronal viability of cultured cortical neurons by approximately 20% compared to untreated cells (A). When neurons were pre-treated with 1 μM Aβ1-40 for seven days, challenge with 200 μM glutamate for 24 hours resulted in a comparable degree of neuronal death compared to unchallenged, Aβ1-40 -treated cells (B). *P < 0.05 between treatments. All data are means ± SEM, n = 6.

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Molecular Neurodegeneration

ISSN: 1750-1326