Fig. 6

CD36 deletion in BAM prevents cognitive dysfunction in 15-month-old Tg2576 mice. A Escape latency is increased in WT → Tg2576 and normalized in CD36^−/− → Tg2576 chimeras. Similarly, CD36^−/− → Tg2576 chimeras identify the target quadrant more reliably at the probe test. B Nest building abilities are improved in CD36^−/− → Tg2576 chimeras, compared to WT → Tg2576 chimeras, as shown by a significantly higher nesting score and % shredded nestlets. N = 10/group; data were analyzed by two-way ANOVA and Tukey’s test, except for the acquisition test which was analyzed by two-way ANOVA with repeated-measures and Tukey’s test. Data presented as mean ± SEM