Fig. 8

The subcluster-specific analysis identifies specific and functional cell subclusters after MLKL deficiency in the A53T transgenic mice. a, c, e. UMAP visualization of subclusters of neurons (a), microglia (c), and astrocytes (e). The frequency distribution of each subcluster between the Tg-Mlkl+/+ and Tg-Mlkl−/− mice was shown at the bottom. b, d, f. Significantly enriched genes in the neurons (b), microglia (d), and astrocyte subclusters (f)