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Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits

Fig. 3

Tardbp localization in CytoTDP fish. A Immunohistochemical stainings of brain (including telencephalon, tectum, hypothalamus, cerebellum and hindbrain) and spinal cord paraffin sections of 5 dpf CytoTDP fish and Control fish show decreased level of Tardbp in the nucleus and increased cytoplasmic Tardbp expression in CytoTDP fish. Black boxes indicate magnified area. Scale bar = 100 μm. B Immunofluorescence stainings of 5 dpf CytoTDP fish and Control fish brain with Tardbp antibody (green) and DAPI (blue) highlighting the relocalization of Tardbp in CytoTDP line. Scale bar = 10 μm

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Molecular Neurodegeneration

ISSN: 1750-1326