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Fig. 4 | Molecular Neurodegeneration

Fig. 4

From: Proteomic analysis of APOEε4 carriers implicates lipid metabolism, complement and lymphocyte signaling in cognitive resilience

Fig. 4

Association of candidate proteins with incident all-cause, Alzheimer’s, and vascular dementia in the UK Biobank. A. Association of APOEε4 candidate proteins with incident dementia in the UK Biobank. B. Association of APOEε3 candidate proteins with incident dementia in the UK Biobank. Hazard ratios were derived from Cox proportional hazards models adjusted for age, sex, education study site, BMI, kidney function (eGFR), diabetes, and cholesterol. Pink circles represent statistical significance at an unadjusted P < 0.05. A bolded protein name indicates significant effect modification by APOEε4 genotype in the WHIMS discovery analyses

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Molecular Neurodegeneration

ISSN: 1750-1326