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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Proteomic analysis of APOEε4 carriers implicates lipid metabolism, complement and lymphocyte signaling in cognitive resilience

Fig. 5

Association of resiliency-associated proteins with plasma ADRD biomarkers

A. Age-adjusted correlation between plasma protein level and plasma Aß42/40, tau, NfL, IL6 and Aß42/42 to tau ratio for APOEe4 candidate proteins. B. Age-adjusted correlation between plasma protein level and plasma Aß42/40, tau NfL, IL6 and Aß42/42 to tau ratio for APOEe3 candidate proteins. The heatmaps display the results in the full sample, among APOEe4 carriers, and among APOEe3 carriers. Bolded protein name indicates significant effect modification by APOE genotype in the discovery (WHIMS) analyses

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Molecular Neurodegeneration

ISSN: 1750-1326