Table 2 Sample characteristics of 30 symptomatic former national football league players
From: 18F-MK-6240 tau PET in patients at-risk for chronic traumatic encephalopathy
Demographics | Former NFL Players N = 30 | Controls N = 40 |
|---|---|---|
Age, mean (SD) years | 58.9 (7.8) | 65.7 (6.3) |
Education, mean (SD) years | 16.6 (1.8) | 17.3 (3.0) |
Sex, n (%) male | 100 | 100 |
Race | ||
 Black, n (%) | 13 (43.3) | 1 (2.5) |
 White, n (%) | 17 (56.7) | 39 (97.5) |
Athletics | ||
 Total years of football, mean (SD) | 18.3 (4.3) | – |
 Total years played in the NFL, mean (SD) | 7.3 (3.9) | – |
 Age of first exposure to football, mean (SD) | 11.3 (2.4) | – |
Primary position in the NFL | – | |
 Tackle, n (%) | 3 (10.0) |  |
 Center, n (%) | 3 (10.0) |  |
 Tight End, n (%) | 3 (10.0) |  |
 Full Back, n (%) | 2 (6.7) |  |
 Running Back, n (%) | 1 (3.3) |  |
 Wide Receiver, n (%) | 1 (3.3) |  |
 Defensive Tackle, n (%) | 2 (6.7) |  |
 Other Defensive Lineman, n (%) | 1 (3.3) |  |
 Middle Linebacker, n (%) | 2 (6.7) |  |
 Other Linebacker, n (%) | 4 (13.3) |  |
 Cornerback, n (%) | 4 (13.3) |  |
 Safety, n (%) | 2 (6.7) |  |
 Free Safety, n (%) | 1 (3.3) |  |
 Other Defensive Back, n (%) | 1 (3.3) |  |
Diagnosis | ||
 Traumatic Encephalopathy Syndrome, n (%) | 22 (73.3) | – |
 Level of CTE certainty | – | |
 Suggestive, n (%) | 5 (16.7) | – |
 Possible, n (%) | 6 (20.0) | – |
 Probable, n (%) | 11 (36.7) | – |
Cognitive Diagnosis | Â | |
 Cognitively normal, n (%) | 9 (30.0) | 100 |
 MCI Amnestic, single domain, n (%) | 4 (13.3) | 0 |
 MCI Amnestic, multiple domains, n (%) | 5 (16.7) | 0 |
 MCI Non-amnestic, single domain, n (%) | 1 (3.3) | 0 |
 MCI Non-amnestic, multiple domains, n (%) | 3 (10.0) | 0 |
 Cognitively impaired, not MCI, n (%) | 3 (10.0) | 0 |
 Dementia, n (%) | 5 (16.7) | 0 |
Global CDR score | – | |
 0 | 7 (23.3) | – |
 0.5 | 18 (60.0) | – |
 1.0 | 5 (16.7) | – |
 CDR sum of boxes, mean (SD) | 1.78 (1.77) | – |
Elevated 18F-Florbetapir, n (%) | 0 | 1 (2.5) |