Skip to main content
Fig. 3 | Molecular Neurodegeneration

Fig. 3

From: Network analysis of the cerebrospinal fluid proteome reveals shared and unique differences between sporadic and familial forms of amyotrophic lateral sclerosis

Fig. 3

CSF Network Modules representing diverse biology vary across ALS subgroups. a. Eigenproteins for each of the CSF proteome modules (n = 12) were compared across control and ALS disease sub-type by one-way ANOVA. Hub proteins and GO terms for each module are highlighted. b. Differentially abundant proteins from each subgroup compared to controls for C9 ALS, Sporadic ALS and C9 Asymptomatic were mapped by module. Symptomatic vs asymptomatic C9orf72 differences were also included. The height of the bars represents the fraction of module member proteins that were differentially abundant. The bars are color coded by heatmap for average log2 difference in abundance, where red represents an increase in abundance, and blue represents a decrease in abundance

Back to article page

Molecular Neurodegeneration

ISSN: 1750-1326