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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Network analysis of the cerebrospinal fluid proteome reveals shared and unique differences between sporadic and familial forms of amyotrophic lateral sclerosis

Fig. 5

Synthetic eigenproteins indicate variation between different forms of ALS, relative to controls. a. Relationship between symptom status (asymptomatic C9orf72, asymptomatic SOD1, C9orf72 ALS, SOD1 ALS, sporadic ALS) modules was evaluated by cross referenced trait values with module proteins using a Biweight midcorrelation (BiCor) analysis. Significance as determined by BiCor are denoted by overlain asterisks; *p < 0.05, **p < 0.01, ***p < 0.001. b. Synthetic eigenproteins for each of the CSF proteome modules (n = 12) were compared across control and ALS disease sub-type by one-way ANOVA

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Molecular Neurodegeneration

ISSN: 1750-1326