Fig. 3
From: Molecular mechanisms and consequences of TDP-43 phosphorylation in neurodegeneration
Phosphomimic TDP-43 variants used in literature. Amino acid substitution can replace serine (purple) with aspartic acid (blue) to mimic or alanine (grey) to prepare phosphorylation. B Phosphomimic TDP-43 variants used to study C-terminal TDP-43 phosphorylation. Figure constructed using biorender.com