Fig. 8

EET treatment promotes microglial phagocytosis and clearance. (A) Representative images of fluorescent Tau PFF (green) in Iba1 (red) positive primary microglia cultures treated with vehicle or 10 µM EET for 18 h, incubated with PFF for 6 h and imaged immediately (0 h) or after 24 h. Scale bar: 50 µm. (B) Quantification of mean intensity of PFF-Tau per cell at 0 h. Veh: n = 30 images; EET: n = 35 images. (C) Quantification of relative mean intensity of PFF-Tau per cell at 24 h. Veh: n = 32 images; EET: n = 29 images. Data are presented as mean ± SEM. ***p < 0.001 by Student’s t test